The Spread of Syphilis in Modern Society and Countermeasures

An Introduction to Syphilis in Japan

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. In Japan, while the number of cases had significantly decreased in the past, there has been an upward trend in infections in recent years.

What is Syphilis: Basic Knowledge

Syphilis is known for causing a variety of symptoms and can lead to serious health problems if left untreated.

About the Bacterium Causing Syphilis

Syphilis is caused by the spirochete bacterium Treponema pallidum. It is primarily transmitted through sexual activity, entering the body through small cuts or mucous membranes of the infected person.

Routes of Infection and Initial Symptoms

The most common route of transmission is sexual contact, but transmission through blood and vertical transmission from pregnant women to their fetus is also possible. The initial symptom is often a painless ulcer known as a chancre.

The History and Current State of Syphilis

Historically, syphilis has seen numerous epidemics, but cases significantly decreased following the discovery of antibiotics. However, in recent years, there has been a rise in the number of infections within Japan.

Past Epidemics and Their Impact Today

Past epidemics had a significant social impact, but now early detection and treatment of infections are possible. Yet, there has been a decline in awareness, particularly among young people, where an increase in infections has been observed.

Statistical Data on Syphilis in Japan

Since the 2010s, there has been an increase in reported cases in Japan, particularly among sexual minorities and young people. Infection data in the country indicate that there is an increase in syphilis reports, especially in urban areas.

Symptoms and Progression of Syphilis

Symptoms of syphilis change over time after infection. Primary syphilis typically presents with a chancre about three weeks post-infection, during which time the risk of transmitting the disease is highest. Even if the chancre heals naturally, the bacteria remain in the body, potentially progressing to secondary and tertiary syphilis.

Identification of Primary Syphilis

The characteristic symptom of primary syphilis is a chancre, which is usually painless. The ulcer can appear singularly or multiply at the site of infection and can heal naturally within weeks, but the infection persists internally.

Signs of Secondary Syphilis

Secondary syphilis is characterized by widespread red rashes, often also appearing on the palms and soles of the feet. Other symptoms can include fever, headaches, muscle aches, and sore throat, which typically disappear after several weeks to months.

Latent Syphilis and Tertiary Syphilis

Latent syphilis shows no symptoms and can vary in duration from weeks to decades. Tertiary syphilis, on the other hand, can occur years after the infection and cause serious damage to the heart, brain, and other organs.

Testing and Diagnosis of Syphilis

Syphilis is typically diagnosed through blood tests. If the presence of a chancre is suspected, direct sampling from the lesion for darkfield microscopy examination is also employed.

Testing Methods and Their Importance

In the early stages, syphilis can be diagnosed through specific antibody tests, which include non-treponemal and treponemal tests, each suitable for different stages of the infection.

Treatment After Diagnosis

Prompt treatment is essential once syphilis is diagnosed. In cases of primary syphilis, antibiotics such as penicillin can be effective, and early treatment often leads to a complete cure.

The Current State and Issues in Syphilis Treatment

The standard treatment for syphilis is penicillin injections, but there are issues with antibiotic resistance and penicillin allergies. Special treatment plans must be considered for pregnant women to prevent fetal impact.

Antibiotic Treatment

While penicillin treatment is very effective against syphilis, alternative medications are necessary for those with allergies. The emergence of syphilis strains resistant to antibiotics is also a concern.

Prevention and Social Challenges

Prevention includes the practice of safe sex and regular testing. However, the lack of sexual education and stigma, and the absence of regular testing make it difficult to prevent syphilis and detect it early.

It is recommended to get tested regularly after sexual contact, not just when symptoms appear.


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